Gynecologist & Obstetrician | MD Professor |
Reproductive Endocrinology, Infertility and
Endometriosis Specialist

His main interest areas:



Polycystic Ovary Syndrome, Endometriosis, Contraception, Menopause and treatment




Laparoscopy, Hysteroscopy, Hysterectomy, Myomectomy








Pregnancy and Delivery




Recurrent Pregnancy Loss




Oocyte Freezing




Chronic Pelvic Pain




Ovarian Cysts




Abnormal Uterine Bleeding




Uterine Malformations

Engin Oral M.D. has been working in the field of obstetrics and gynecology since 1993 and giving
lectures at Istanbul University Cerrahpasa Medical Faculty since 1997. As of november 2018, Prof. Dr.
Oral is the current president of the European Endometriosis League.

He is also the founder of Endometriosis & Adenomyosis Society of Turkey and he is currently
the vice president of the society.

He is seeing his patients in his private offices located in Nisantasi and Florya.



Education and Training

  • Postdoctoral Fellow Obstetrics and Gynecology Department division of Medicine
    Reproductive Endocrinology Department (Mentors David L Olive and Aydın Arıcı) Yale
    University Faculty USA 1995-1996
  • Resident Obstetrics and Gynecology Department of Istanbul University Cerrahpaşa
    Medical Faculty, 1988 -1992
  • MD Istanbul University, Istanbul Medical Faculty (graduated from the university in
    third place.) 1982-1988
  • High School Kabataş Erkek, İstanbul, 1979-1982


Professional Experience

  • Chief Resident Department of Obstetrics and Gynecology, Istanbul University
    Cerrahpaşa Medical Faculty, 1993 January-1994 December
  • Chief Resident Department of Obstetrics and Gynecology, Istanbul University
    Cerrahpaşa Medical Faculty, July-October 1997
  • Associate Professor Division of Reproductive Endocrinology, Department of
    Obstetrics and Gynecology Istanbul University Cerrahpaşa Medical Faculty,
  • Professor Division of Reproductive Endocrinology, Department of Obstetrics and
    Gynecology Istanbul University Cerrahpaşa Medical Faculty, 2003-…


Board Member

  • President of European Endometriosis League (EEL)
  • Founding Chairman of the Executive Committee of the Turkish Endometriosis and Adenomyosis Association
  • Member of the Executive Committee of Turkish Gynecology and Obstetrics Society (TJOD) – Istanbul
  • Member of the Executive Committee of Turkish Society of Menopause and Osteoporosis


International Societies – Professional

  • Asian Society of Endometriosis and Adenomyosis
  • European Society of Human Reproduction and Embryology (ESHRE)
  • American College of Obstetricians and Gynecologists (ACOG) (Associate Membership
  • European Menopause and Andropause Society (EMAS)
  • International Menopause Society (IMS)
  • World Endometriosis Society (WES)


Organized International Scientific Meetings on

  • 4th European Congress on Endometriosis Vienna, 2018 (Secretary Somatic
  • 3rd European Endometriosis League, November 17-19, 2016, Budapest, Hungary (Chairperson of National Meeting)
  • ESHRE CAMPUS 2016: ‘’Controversies in Endometriosis and Adenomyosis’’, February
    26-28, 2016, Istanbul-Turkey (Symposium President)
  • Deep Endometriosis International, ”Multidisciplinary Approach” Symposium,
    January 18-19, 2014, Istanbul-Turkey (Symposium President)
  • 2nd European Endometriosis League, November 28-30, 2013, Berlin, Germany (Chairperson of National Meeting)
  • ACE 2012 (2nd Asian Conference on Endometriosis) November 9-11, 2012,
    Istanbul-Turkey, (Conference President)



English, Turkish

Prof. Oral is the author of 54 internationally cited

Peer-Reviewed Publications
  1. Usta T., Karacan T., Hanli U., Cansu E., Oral E. Hysteroscopic management of a
    juvenile cystic adenomyosis, J Endometriozis and Pelvic Pain Disorders, 2018 Jun;
    vol10:123-123, doi:org/10.1177/228402651877879.
  2. Kaya C, Alay I, Guraslan H, Gedikbasi A, Ekin M, Ertaş Kaya S, Oral E, Yasar L,The
    Role of Serum Caspase 3 Levels in Prediction of Endometriosis Severity. Gynecol Obstet
    Invest. 2018 Aug 2:1-10. doi: 10.1159/000489494.
  3. Sofiyeva N, Oral E. Letter from original author re. Does telomerase activity have an
    effect on infertility in patients with endometriosis? Methodological issues. Eur J
    Obstet Gynecol Reprod Biol. 2017 Sep; 216:259-260. doi: 10.1016/j.ejogrb.2017.07.009. Epub 2017 Jul
    12. No abstract available.
  4. Sofiyeva N, Ekizoglu S, Gezer A, Yilmaz H, Kolomuc Gayretli T, Buyru N, Oral E. Does
    telomerase activity have an effect on infertility in patients with endometriosis?
    Eur J Obstet Gynecol Reprod Biol. 2017 Jun; 213:116-122. doi: 10.1016/j.ejogrb.2017.04.027. Epub 2017 Apr
  5. Oral E, Aydogan Mathyk B, Aydogan BI, Acıkgoz AS, Erenel H, Celik Acıoglu H, Anık
    Ilhan G, Dane B, Ozel A, Tandogan B, Cakar E, Isci H, Kayan B, Aslan H, Ekiz A, Sancak
    S, Celik A, Yoldemir T, Uzun O, Erdogan MF. Iodine status of pregnant women in a
    metropolitan city which proved to be an iodine-sufficient area. Is mandatory salt
    iodisation enough for pregnant women? Gynecol Endocrinol. 2016;32(3):188-92. doi:
    10.3109/09513590.2015.1101443. Epub 2015 Oct 22.
  6. Gezer A, Oral E. Progestin therapy in endometriosis. Womens Health (Lond). 2015
    Aug;11(5):643-52. doi: 10.2217/whe.15.42. Epub 2015 Sep 21. Review.
  7. Oral E, Demir B, Inceboz U. Endometriosis and ovarian reserve. Womens Health (Lond).
    2015 Aug;11(5):671-5. doi: 10.2217/whe.15.53. Epub 2015 Sep 7. Review.
    Inceboz U, Oral E. Foreword. Womens Health (Lond). 2015 Aug;11(5):575. doi:
    10.2217/whe.15.61. Epub 2015 Sep 7.
  8. Sahmay S, Usta TA, Zebitay G, Senturk LM, Oral E, Ocal P, Idil M, Irez T. Comparison
    of follitropin alfa and urinary gonadotropins in IVF cycles.Minerva Ginecol.
    2014 Aug;66(4):341-6.
  9. Elter K, Oral E. Surgical treatment before assisted reproductive technologies. Semin
    Reprod Med. 2014 Jul;32(4):253-61. doi: 10.1055/s-0034-1375177. Epub 2014 Jun 11.
  10. Findikli N, Oral E. Time-lapse embryo imaging technology: does it improve the
    clinical results? Curr Opin Obstet Gynecol. 2014 Jun;26(3):138-44. doi: 10.1097/
    GCO.0000000000000072. Review.
  11. Tuten A, Kucur M, Imamoglu M, Oncul M, Acikgoz AS, Sofiyeva N, Ozturk Z, Kaya B,
    Oral E. Serum YKL-40 levels are altered in endometriosis. Gynecol Endocrinol. 2014
    May;30(5):381-4. doi: 10.3109/09513590.2014.887671. Epub 2014 Feb
  12. Sahmay S, Guralp O, Aydogan B, Cepni I, Oral E, Irez T. Anti-Mullerian hormone and
    polycystic ovary syndrome: assessment of the clinical pregnancy rates in in vitro
    fertilization patients. Gynecol Endocrinol. 2013 May;29(5):440-3. doi:
    10.3109/09513590.2013.769519. Epub 2013 Mar 6.
  13. Irez T, Usta TA, Zebitay G, Oral E, Senol H, Sahmay S. Evaluation of subgroups of the
    human sperm hypoosmotic swelling test in normozoospermic male cases with recurrent
    fertilization failure: a prospective case-controlled study. Arch Gynecol Obstet.
    2013 Apr;287(4):797-801. doi: 10.1007/s00404-012-2634-6. Epub 2012 Nov 18.
  14. Kumbak B, Oral E, Bukulmez O. Female obesity and assisted reproductive technologies.
    Semin Reprod Med. 2012 Dec;30(6):507-16. doi: 10.1055/s-0032-1328879. Epub 2012 Oct
    16. Review.
  15. Sahmay S, Demirayak G, Guralp O, Ocal P, Senturk LM, Oral E, Irez T. Serum
    anti-mullerian hormone, follicle stimulating hormone and antral follicle count
    measurement cannot predict pregnancy rates in IVF/ICSI cycles. J Assist Reprod Genet.
    2012 Jul;29(7):589-95. doi:10.1007/s10815-012-9754-6. Epub 2012 Apr 11.
  16. Usta T, Oral E. Is the measurement of anti-Mullerian hormone essential? Curr Opin
    Obstet Gynecol. 2012 Jun;24(3):151-7. doi: 10.1097/GCO.0b013e3283527dcf. Review.
  17. Yoldemir T, Oral E. Has fertility declined in recent decades? Curr Opin Obstet Gynecol.
    2012 Jun;24(3):119-26. doi: 10.1097/GCO.0b013e32835213f1. Review.
  18. Kucuk M, Halil S, Ocer F, Oral E. Labial fusion first diagnosed during pregnancy with
    voiding difficulty and its management: a case report. Clin Exp Obstet Gynecol.
  19. Cetinkaya F, Gelen SA, Kervancioglu E, Oral E. Prevalence of asthma and other allergic
    diseases in children born after in vitro fertilisation. Allergol Immunopathol (Madr).
    2009 Jan-Feb;37(1):11-3.
  20. Kumbak B, Oral E.Quality of residual follicles may depend on the etiology of
    “declining” ovarian function? Fertil Steril. 2007 Nov;88(5):1480-1; author reply 1481.
  21. Oral E, Elter K. The impact of cesarean birth on subsequent fertility. Curr Opin
    Obstet Gynecol. 2007 Jun;19(3):238-43. Review.
  22. Kumbak B, Oral E, Karlikaya G, Lacin S, Kahraman S. Serum oestradiol and beta- HCG
    measurements after day 3 or 5 embryo transfers in interpreting pregnancy outcome.
    Reprod Biomed Online. 2006 Oct;13(4):459-64.
  23. Kumbak B, Oral E, Kahraman S, Karlikaya G, Karagozoglu H. Young patients with
    diminished ovarian reserve undergoing assisted reproductive treatments: a
    preliminary report. Reprod Biomed Online. 2005 Sep;11(3):294-9.
  24. Oral E, Genç MR. Hormonal monitoring of the first trimester of pregnancy. Obstet Gynecol
    Clin North Am. 2004 Dec;31(4):767-78, x. Review.
  25. Aksu F, Gezer A., Oral E., Seventeen-year review of hysterectomy procedures in a
    university clinic in İstanbul (1985-2001) rch Obstet Gynecol, 2004.
  26. Oral E, Ilvan S, Tustas E, Korbeyli B, Kosebay D, Prevalence of endometriosis in
    malignant epithelial ovary tumours Research article Eur J Obstet Gynecol Reprod Biol.
    2003 Jul;109(1):97-101.
  27. Oral E1, Gezer A, Cagdas A, Pakkal N. Oxytocin İnfusion in Labor: the effect
    different indications and the use of different diluents on neonatal bilirubin
    levels. Arch Gynecol Obstet. 2003 Jan;267(3):117-20.
  28. Oral E, Yetis O, Elibol F, Senol H, Irez T, Aksu FM. Assessment of human sperm
    morphology by strict criteria: comparison of wet preparation versus stained with the
    modified Diff-Quik method. Arch Androl. 2002 Jul-Aug;48(4):307-14.
  29. Oral E, Cağdaş A, Gezer A, Kaleli S, Öçer F, Perinatal and Maternal Outcomes of Fetal
    Macrosomia Eur J Obstet Gynecol Reprod Biol. 2001 Dec; 99(2): 167-171.
  30.  Oral E, Cağdaş A, Gezer A, Kaleli S, Aydin Y, Oçer F. Hematological abnormalities in
    adolescent menorrhagia. Arch Gynecol Obstet. 2002 Apr;266(2):72-4.
  31. Erel CT, Oral E, Senturk LM, Aksu MF. Craniopharyngioma and Bardet-Biedl syndrome.
    A case report. J Reprod Med. 2001 May;46(5):501-3.
  32. Akçay T, Dinçer Y, Kayali R, Colgar U, Oral E, Cakatay U. Effects of hormone replacement
    therapy on lipid peroxides and oxidation system in postmenopausal women. J Toxicol
    Environ Health A. 2000 Jan 14;59(1):1-5.
  33. Sahmay S, Kaleli S, Oral E, Alper T, Unal O, Karacan I, Atasu T. Effect of different
    types of intrauterine devices on intrauterine activity. Int J Fertil Womens
    Med. 1999 May-Jun;44(3):150-5.
  34. Öçer F, Kaleli S, Budak E, Oral E. Fetal Weight Estimation and Prediction of Fetal
    Macrosomia in Nondiabetic Pregnant Women Research article Eur J Obstet Gynecol Reprod
    Biol.1999 Mar; 83(1):47-52.
  35. Erel CT, Senturk LM, Oral E, Mutlu H, Colgar U, Seyisoglu H, Ertungealp E. Results of the
    ACTH stimulation test in hirsute women. J Reprod Med. 1999 Mar; 44(3):247-52.
  36. Bahtiyar MO, Seli E, Oral E, Senturk LM, Zreik TG, Arici A. Follicular fluid of women
    with endometriosis stimulates the proliferation of endometrial stromal cells.
    Hum Reprod. 1998 Dec;13(12):3492-5.
  37. Kaleli S, Erel CT, Oral E, Elter K, Akman C, Colgar U. Ovarian stromal hypertrophy in
    polycystic ovary syndrome. J Reprod Med. 1998 Oct;43(10):893-7.
  38. Erel CT, Senturk LM, Oral E, Colgar U, Ertungealp E. Adrenal androgenic response to
    2-hour ACTH stimulation test in women with PCOS. Gynecol Endocrinol. 1998
  39. Zeyneloglu HB, Senturk LM, Seli E, Oral E, Olive DL, Arici A. The role of monocyte
    chemotactic protein-1 in intraperitoneal adhesion formation. Hum Reprod. 1998
  40. Arici A, Seli E, Senturk L,Gutierrez L, Oral E, Taylor H, Interleukin-8 in the Human
    Endometrium The Journal of Clinical Endocrinology & Metabolism, Volume 83, Issue
    5, 1 May 1998, Pages 1783–1787.
  41. Arici A, Seli E, Zeyneloglu HB, Senturk LM, Oral E, Olive DL. Interleukin-8 induces
    proliferation of endometrial stromal cells: a potential autocrine growth factor. J Clin
    Endocrinol Metab. 1998 Apr;83(4):1201-5.
  42. Oral E, Seli E, Bahtiyar MO, Jones EE, Arici A. Growth-regulated alpha expression in
    human preovulatory follicles and ovarian cells. Am J Reprod Immunol. 1997 Jul;
  43. Arici A, Oral E, Attar E, Tazuke S, Olive D. Monocyte chemotactic protein-1 concentration
    in peritoneal fluid of women with endometriosis and its modulation of
    expression in mesothelial cells Research article Fertil Steril. 1997 Jun;
  44. Arici A, Oral E, Bahtiyar O, Engin O, Seli E, Jones EE. Leukaemia inhibitory factor
    expression in human follicular fluid and ovarian cells. Hum Reprod. 1997
  45. Oral E, Arici A. Pathogenesis of Endometriosis, Research article Obstetrics
    and Gynecology Clinics of North America, 1997 Jun; 24(2): 219-233.
  46. Arici A, Oral E, Bukulmez O, Buradagunta S, Bahtiyar O, Jones EE. Monocyte chemotactic
    protein-1 expression in human preovulatory follicles and ovarian cells. J Reprod
    Immunol. 1997 Feb;32(3):201-19.
  47. Oral E, Seli E, Bahtiyar MO, Olive DL, Arici A Growth-regulated alpha expression in the
    peritoneal environment with endometriosis. Obstet Gynecol. 1996 Dec;88(6): 1050-6.
  48. Erel CT, Kaleli S, Oral E, Engür A, Eren T, Calay Z, Aydinli K. DNA ploidy of ectopic
    pregnancy and first trimester spontaneous abortion investigated by flow cytometry.
    Acta Obstet Gynecol Scand. 1996 Nov;75(10):881-5.
  49. Oral E, Arici A, Olive D, Huszar G. Peritoneal fluid from women with moderate or
    severe endometriosis inhibits sperm motility: the role of seminal fluid
    components Research article Fertil Steril. 1996 Nov; 66(5):787-792.
  50. Arici A, Oral E, Bukulmez O, Buradagunta S, Engin O, Olive DL. Interleukin-8 expression
    and modulation in human preovulatory follicles and ovarian cells.Endocrinology.
    1996 Sep;137(9):3762-9.
  51. Oral E, Olive DL, Arici A. The peritoneal environment in endometriosis.Hum Reprod
    Update. 1996;2(5):385-398.
  52. Oral E, Arici A. Peritoneal growth factors and endometriosis Semin Reprod Endocrinol.
  53. Arici A, Oral E, Bukulmez O, Duleba A, Jones E The effect of endometriosis on
    implantation: results from the Yale University in vitro fertilization and embryo
    transfer program Research article Fertil Steril. 1996 Mar; 65(3): 603-607.
  54. Sahmay S, Oral E, Saridogan E, Senturk L, Atasu T. Endometrial biopsy findings in
    infertility: analysis of 12,949 cases. Int J Fertil Menopausal Stud. 1995 Nov-Dec;

Nişantaşı Office

Adress Vali Konağı Street, Saroğlu
Apt., Number: 83 Floor:3/10
Nisantasi/ Istanbul
+90 212 343 20 00
+90 212 343 20 01
+90 212 343 20 02
+90 533 397 50 46

Florya Office

Adress Florya Street, Şenlikköy
District, Seren Apt.,
Number:8 Floor: 2 / 5 Florya
– Istanbul
+90 212 663 88 98
+90 212 663 98 77
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